Laboratory of Computational Biology

Description of the Group

We develop and use computational tools for studies of 3D structure of biomolecules and their dynamics. Our interests embrace broad aspects of computational biology, from molecular simulations to data analysis. Read more at the laboratory website: http://lcbio.pl/

Research Activities

structure prediction of proteins and their complexes
molecular docking: protein-peptide, protein-protein, protein-small ligand
molecular dynamics: all-atom and coarse-grained methods
development and design of computational tools: easy-to-use web servers and advanced standalone applications
structure-based drug design
rational protein design
bioinformatic support of experimental studies
biostatistics
scientific databases
big data analysis

Offer

Support of drug design using computer methods
Support for structural biology research by using bioinformatic methods and molecular modeling
Development of software dedicated to simulation of proteins and other biological systems
Development of web-servers for computer support of drug design and biological research support
Development of biological databases
Analysis and prediction of protein properties
Protein modeling and engineering
Statistical analysis of biological data
Use of a supercomputer to simulate biological systems
Use of a supercomputer for biological data analysis
Visualization of biological data

Team Leader

Sebastian Kmiecik received his doctorate in 2007 at the Faculty of Chemistry of the University of Warsaw. In 2007-2010, he worked in Selvita, a biotechnology company, where he directed R&D projects that included software development and drug design support services. From 2010, he worked on new methods of multiscale modeling of proteins at the Faculty of Chemistry, University of Warsaw. In 2015, Sebastian Kmiecik received a D.Sc. degree, and in 2016 the award of the Minister of Science and Higher Education for his scientific achievements of the first degree.