W ostatnim numerze Journal of the American Chemical Society (JACS), pojawił się artykuł autorstwa pracowników grupy badawczej Laboratorium Chemii Supramolekularnej z CNBCh UW,
której kierownikiem jest dr Michał Chmielewski.

JACS to jeden z najbardziej prestiżowych czasopism związanych z wiedzą chemiczną.

A Photoswitchable Heteroditopic Ion-Pair Receptor
Zoran Kokan, Michał Chmielewski

Link do artykułu:
https://pubs.acs.org/doi/10.1021/jacs.8b08689

Abstract:

 

Abstract Image

 

Designing light-switchable heteroditopic receptors is challenging because it necessitates simultaneous (de)activation of two separate binding sites. Herein, we present the first photoswitchable heteroditopic ion-pair receptor in which both cation and anion binding sites are simultaneously and reversibly switched OFF and ON by a single photoswitch. Our receptor is simple, low molecular weight, and readily synthesized from commercially available precursors. Single-crystal X-ray structures and NMR spectroscopic titrations support ion-pair binding to the receptor both in the solid state and in solution, with strong positive cooperativity between the cation and anion binding. The receptor can be completely switched OFF by UV light-triggered photoisomerization of an acylhydrazone C═N double bond and remains kinetically stable in the deactivated form due to an intramolecular hydrogen bond. Its re-activation could be achieved by light irradiation or, more effectively, by fast acid-catalyzed back-isomerization. Our simple photoswitchable ion-pair receptor may serve as a blueprint for the design of new generations of switchable receptors, transporters, soft materials, and self-assembled systems, where incorporation of a functional heteroditopic ON/OFF photoswitch has been challenging up to now.

 

 

Laboratorium Chemii Supramolekularnej

poniedziałek, Listopad 26, 2018 - 10:27