Research group Laboratory of Bionanostructures works on electron transfer processes in supramolecular and biomolecular systems, catalysis, molecular exploration of phase boundaries, and on bioelectrocatalysis. Group members study molecular self-assembly in solid and liquid substrates, properties of mono- and multilayered Langmuir-Blodgett films. Moreover, they are interested in electrochemistry of molecular machines and macrocyclic receptors, and electrochemical sensors that, due to wide spectra of possible applications, can be used in medicine and environmental assessments.


Professor Renata Bilewicz



Professor Renata Bilewicz,
phone 22 822 02 11 wew. 345,
room 345 Wydział Chemii.

Dorota Matyszewska,
Sylwia Dramińska,
Maciej Karaśkiewicz.
phone: 22 55 26547, CNBCh UW room 4.04


Laboratory of Bionanostructures carries out research on the transport effectiveness of chosen cytotoxic agents (doxorubicin, daunomycin) through model cellular membranes. Members of this laboratory also work on the preparation of neurotransmitter sensor. So far, they have prepared a method for measurements of catechol concentration. An amperometric sensor, produced during their studies, was combined with a biobattery, using a zinc disc as an anode and carbon paper covered with multi-walled naphtylated carbon nanotubes with adsorbed lactase of Trametes versicolor as a cathode (lactase reduces oxygen directly from water). The biobattery works in a flow-through system, and oxygen, used as a cathode substrate, is continuously delivered to the reaction chamber. A system consisting of a biobattery, minipotentiostat and sensor was used for the detection of catechol. This system was characterized by the chronoamperometric method. The response of the chronoamperometric sensor is related to an increase in the current and catechol concentration in solution. BVT electrodes were used to prepare the catechol sensor. Amperometric measurements were carried out with BVT potentiostat, that together with tri-electrode BVT sensor, was computer –powered.

The laboratory of Bionanostructures is equipped with: (1) Langmuir bath with the possibility of transferring films onto solid substrates; this apparatus allows preparation of films of amphiphilic substances, surfactants on the water-air interface, study interactions of different substances (e.g. drugs, oxines, enzymes, peptides) with model biological membranes, and transfer of model films onto solid substrates; (2) the Brewster angle microscope, giving the possibility to visualize morphological changes in a film on the interface between water and air in real time (e.g. observation of domain formation); (3) auto-nulling spectroscopic imaging ellipsometer, enabling measurements of film thickness (at phase boundaries and on solid substrates) and thickness mapping, potentiostat (electrochemical techniques – voltamperometry and chronoamperometry).